Toxicology – the research of how chemical compounds work together with organic techniques – has clear relevance to human well being and illness. Persistent publicity to pure and artificial chemical compounds is an unavoidable a part of residing on our planet; but, we perceive little or no concerning the results of publicity to the overwhelming majority of chemical compounds. Whereas epidemiological research can present robust statistical inference linking chemical publicity to illness, analysis in mannequin techniques is crucial to elucidate the mechanisms of motion and to foretell outcomes.
Most analysis in toxicology makes use of a handful of mammalian fashions that symbolize a number of distinct branches of the evolutionary tree. This slender focus constrains the understanding of chemical-induced illness processes and techniques which have developed in response to exposures. We advocate for casting a wider internet in environmental toxicology analysis to make the most of various mannequin techniques, together with zebrafish, and carry out extra mechanistic research of mobile responses to chemical exposures to shift the notion of toxicology as an utilized science to that of a primary science. This more-inclusive perspective will enrich the sector and may stay central to analysis on chemical-induced illness.
Traditionally, analysis in toxicology has utilized non-human mammalian species, notably rats and mice, to check in vivo the results of poisonous publicity on physiology and conduct. Nevertheless, moral issues and the overwhelming enhance within the variety of chemical compounds to be screened has led to a shift away from in vivo work. The decline in in vivo experimentation has been accompanied by a rise in various strategies for detecting and predicting detrimental results: in vitro experimentation and in silico modeling.
But, these new methodologies can’t substitute the necessity for in vivo work on animal physiology and conduct. The event of recent, non-mammalian mannequin techniques exhibits nice promise in restoring our skill to make use of behavioral endpoints in toxicological testing. Of those techniques, the zebrafish, Danio rerio, is the mannequin organism for which we’re accumulating sufficient information in vivo, in vitro, and in silico to allow us to develop a complete, highthroughput toxicology screening system.
Developmental toxicity of fipronil in early improvement of zebrafish (Danio rerio) larvae: Disrupted vascular formation with angiogenic failure and inhibited neurogenesis.
Fipronil has been extensively utilized in agriculture to forestall aggressive bugs from damaging agricultural merchandise. Fipronil residues flow into within the setting they usually have been detected in non-targeted organisms in aquatic environments. To check the impact of fipronil toxicity on environmental well being, 6 h put up fertilization (hpf) zebrafish embryos have been handled with fipronil for 72 h. LC50 worth was obtained by making use of various concentrations of fipronil to zebrafish embryos for 72 h.
As zebrafish embryos are helpful vertebrate fashions for finding out developmental and genetic findings in toxicology analysis, they have been uncovered to fipronil to check detailed elucidating mechanisms with hazardous finish factors of toxicity. Cell cycle arrest-related apoptosis supported pathological alterations, equivalent to elevated mortality, shortened physique size, and lowered hatchability.
Moreover, noticed coronary heart defects, together with edema and irregular heartbeat have been triggered because of irregular blood circulation. In transgenic zebrafish fashions (fli1:eGFP and olig2:dsRED), disrupted blood vessel formations have been indicated by eGFP+ endothelial cells. Furthermore, neurogenic defects have been noticed by finding out dsRED+ motor neurons and oligodendrocytes. This research demonstrates fipronil accumulation in aquatic setting and its skill to impair important processes, equivalent to angiogenesis and neurogenesis throughout early developmental stage of zebrafish, together with normal developmental toxicity.
Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish.
In aquatic toxicology, maybe no pharmaceutical has been investigated extra intensely than 17alpha-ethinylestradiol (EE2), the lively ingredient of the contraception capsule. On the flip of the century, the fields of comparative endocrinology and endocrine disruption analysis witnessed the emergence of omics applied sciences, which have been quickly tailored to characterize potential hazards related to exposures to environmental estrogens, equivalent to EE2.
Since then, vital advances have been made by the scientific neighborhood, and in consequence, a lot has been realized about estrogen receptor signaling in fish from environmental xenoestrogens. Vitellogenin, the egg yolk precursor protein, was recognized as a significant estrogen-responsive gene, establishing itself because the premier biomarker for estrogenic exposures. Omics research have recognized a plethora of estrogen responsive genes, contributing to a wealth of data on estrogen-mediated regulatory networks in teleosts.
There have been ∼40 research that report on transcriptome responses to EE2 in quite a lot of fish species (e.g., zebrafish, fathead minnows, rainbow trout, pipefish, mummichog, stickleback, cod, and others). Information on the liver and testis transcriptome dominate within the literature and have been the topic of many EE2 research, but there stay information gaps for different tissues, such because the spleen, kidney, and pituitary. Inter-laboratory genomics research have revealed transcriptional networks altered by EE2 remedy within the liver; networks associated to amino acid activation and protein folding are elevated by EE2 whereas these associated to xenobiotic metabolism, immune system, circulation, and triglyceride storage are suppressed.
Zebrafish Growth Hormone Mutant Protein |
20-abx260619 |
Abbexa |
-
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Zebrafish Somatotropin, G113R mutant (GH1) Protein |
abx260619-10g |
Abbexa |
10 µg |
EUR 325 |
Zebrafish Somatotropin, G113R mutant (GH1) Protein |
abx260619-2g |
Abbexa |
2 µg |
EUR 225 |
Zebrafish Growth Hormone mutant (G119R) Recombinant Protein |
500-023 |
ReliaTech |
50 µg |
EUR 278.25 |
Description: Recombinant zebrafish growth hormone mutant G119R (zbGH mutant) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton. |
Zebrafish Growth Hormone mutant (G119R) Recombinant Protein |
500-023S |
ReliaTech |
10 µg |
EUR 178.5 |
Description: Recombinant zebrafish growth hormone mutant G119R (zbGH mutant) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton. |
Recombinant Zebrafish Growth Hormone Mutant |
7-00574 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Zebrafish Growth Hormone Mutant |
7-00575 |
CHI Scientific |
50µg |
Ask for price |
Recombinant Zebrafish Growth Hormone Mutant |
7-00576 |
CHI Scientific |
1mg |
Ask for price |
Recombinant Zebrafish Growth Hormone Mutant |
cyt-709-10g |
ProSpec Tany |
10µg |
EUR 60 |
Recombinant Zebrafish Growth Hormone Mutant |
cyt-709-1mg |
ProSpec Tany |
1mg |
EUR 2300 |
Recombinant Zebrafish Growth Hormone Mutant |
cyt-709-50g |
ProSpec Tany |
50µg |
EUR 145 |
Recombinant Zebrafish GH Protein, Untagged, E.coli-1mg |
QP10635-1mg |
EnQuireBio |
1mg |
EUR 2829.6 |
Recombinant Zebrafish GH Protein, Untagged, E.coli-10ug |
QP10635-10ug |
EnQuireBio |
10ug |
EUR 186 |
Recombinant Zebrafish GH Protein, Untagged, E.coli-50ug |
QP10635-50ug |
EnQuireBio |
50ug |
EUR 241.2 |
Zebrafish GH(Growth Hormone) ELISA Kit |
ELK9404-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Zebrafish GH protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish GH. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish GH in the samples is then determined by comparing the OD of the samples to the standard curve. |
Zebrafish GH(Growth Hormone) ELISA Kit |
ELK9404-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Zebrafish GH protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish GH. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish GH in the samples is then determined by comparing the OD of the samples to the standard curve. |
Zebrafish Talin (TLN) Protein |
20-abx655190 |
Abbexa |
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Talin (TLN) Protein |
abx655190-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Talin (TLN) Protein |
abx655190-50g |
Abbexa |
50 µg |
EUR 5300 |
Zebrafish Growth Hormone Protein |
20-abx260620 |
Abbexa |
-
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Zebrafish Somatotropin (GH1) Protein |
abx260620-10g |
Abbexa |
10 µg |
EUR 325 |
Zebrafish Somatotropin (GH1) Protein |
abx260620-2g |
Abbexa |
2 µg |
EUR 225 |
Danio rerio (zebrafish) VEGFA Protein |
E40PZE003 |
EnoGene |
20ug |
EUR 495 |
Zebrafish Cathepsin L (CTSL) Protein |
20-abx652813 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Cathepsin L1 (CTSL) Protein |
abx652813-5mg |
Abbexa |
5 mg |
EUR 5300 |
Zebrafish Interleukin 15 (IL15) Protein |
20-abx653977 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Interleukin 15 (IL15) Protein |
abx653977-100g |
Abbexa |
100 µg |
EUR 8012.5 |
Zebrafish Interleukin 15 (IL15) Protein |
abx653977-200g |
Abbexa |
200 µg |
Ask for price |
Zebrafish Interleukin 15 (IL15) Protein |
abx653977-50g |
Abbexa |
50 µg |
EUR 3200 |
Zebrafish Interleukin 12B (IL12B) Protein |
20-abx653962 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
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Zebrafish Interleukin 12B (IL12B) Protein |
abx653962-5mg |
Abbexa |
5 mg |
EUR 2112.5 |
Zebrafish Galactosidase Beta (GLb) Protein |
20-abx653494 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Beta-Galactosidase (GLB1) Protein |
abx653494-100g |
Abbexa |
100 µg |
EUR 5300 |
Zebrafish Beta-Galactosidase (GLB1) Protein |
abx653494-200g |
Abbexa |
200 µg |
Ask for price |
Zebrafish Beta-Galactosidase (GLB1) Protein |
abx653494-50g |
Abbexa |
50 µg |
EUR 2112.5 |
Recombinant Zebrafish A1AT Protein (aa 1-124) |
VAng-2983Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 3820.8 |
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2) |
Recombinant Zebrafish A1AT Protein (aa 1-124) |
VAng-2983Lsx-200g |
Creative Biolabs |
200 µg |
EUR 2337.6 |
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2) |
Recombinant Zebrafish A1AT Protein (aa 1-124) |
VAng-2983Lsx-500g |
Creative Biolabs |
500 µg |
EUR 2568 |
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2) |
Zebrafish Growth Hormone Recombinant Protein |
500-022 |
ReliaTech |
50 µg |
EUR 278.25 |
Description: Recombinant zebrafish growth hormone (zbGH) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton. |
Zebrafish Growth Hormone Recombinant Protein |
500-022S |
ReliaTech |
10 µg |
EUR 178.5 |
Description: Recombinant zebrafish growth hormone (zbGH) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton. |
Recombinant Zebrafish Cxadr Protein (aa 23-241) |
VAng-Cr4512-1mgEcoli |
Creative Biolabs |
1 mg (E. coli) |
EUR 4876.8 |
Description: Zebrafish Coxsackievirus and adenovirus receptor homolog (cxadr), recombinant protein. |
Recombinant Zebrafish Cxadr Protein (aa 23-241) |
VAng-Cr4512-500gEcoli |
Creative Biolabs |
500 µg (E. coli) |
EUR 3261.6 |
Description: Zebrafish Coxsackievirus and adenovirus receptor homolog (cxadr), recombinant protein. |
Recombinant Zebrafish ALCAM Protein (aa 25-507) |
VAng-2956Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 6906 |
Description: Recombinant Zebrafish ALCAM is expressed in E. coli. (Uniprot ID: Q90460) |
Recombinant Zebrafish ALCAM Protein (aa 25-507) |
VAng-2956Lsx-500g |
Creative Biolabs |
500 µg |
EUR 4233.6 |
Description: Recombinant Zebrafish ALCAM is expressed in E. coli. (Uniprot ID: Q90460) |
Zebrafish Creatine Kinase, Muscle (CKM) Protein |
20-abx653069 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Zebrafish Creatine Kinase, Muscle (CKM) Protein |
abx653069-100g |
Abbexa |
100 µg |
EUR 5300 |
Zebrafish Creatine Kinase, Muscle (CKM) Protein |
abx653069-200g |
Abbexa |
200 µg |
Ask for price |
Zebrafish Creatine Kinase, Muscle (CKM) Protein |
abx653069-50g |
Abbexa |
50 µg |
EUR 2112.5 |
Zebrafish Bone Morphogenetic Protein 4 (BMP4) Protein |
20-abx652682 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Zebrafish Bone Morphogenetic Protein 4 (BMP4) Protein |
abx652682-5mg |
Abbexa |
5 mg |
EUR 537.5 |
Recombinant Zebrafish VEGF165 Protein (aa 1-188) |
VAng-Cr4056-100g |
Creative Biolabs |
100 µg |
EUR 2841.6 |
Description: Recombinant Zebrafish VEGF165 Protein (Met1-Arg188) was expressed in Baculovirus-Insect Cells, with a molecular weight of 19.2 kDa. (Accession ID: O73682) |
Recombinant Zebrafish VEGF165 Protein (aa 1-188) |
VAng-Cr4056-5g |
Creative Biolabs |
5 µg |
EUR 456 |
Description: Recombinant Zebrafish VEGF165 Protein (Met1-Arg188) was expressed in Baculovirus-Insect Cells, with a molecular weight of 19.2 kDa. (Accession ID: O73682) |
Danio rerio (zebrafish) efnb2a Protein, His Tag |
E40PZE001 |
EnoGene |
20ug |
EUR 495 |
Danio rerio (zebrafish) BMP-2 Protein, Fc Tag |
E40PZE002 |
EnoGene |
20ug |
EUR 495 |
Zebrafish Id1 Rbt pAb, Protein A purified, 25UG |
A014-25UG |
Arbor Assays |
25UG |
EUR 510 |
Zebrafish Anti-Mullerian Hormone (AMH) Protein (BSA) |
20-abx651052 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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|
Zebrafish Anti-Mullerian Hormone (AMH) Protein (OVA) |
20-abx651053 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Fibroblast Growth Factor 6 (FGF6) Protein |
20-abx653400 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Fibroblast Growth Factor 6 (FGF6) Protein |
abx653400-5mg |
Abbexa |
5 mg |
EUR 5300 |
Zebrafish Gonadotropin Releasing Hormone (GnRH) Protein |
20-abx653622 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Angiopoietin-1 Receptor / TIE2 (TEK) Protein |
abx655203-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Angiopoietin-1 Receptor / TIE2 (TEK) Protein |
abx655203-50g |
Abbexa |
50 µg |
EUR 5300 |
OPCA02179-100UG - D2HGDH Recombinant Protein (Zebrafish) |
OPCA02179-100UG |
Aviva Systems Biology |
100ug |
EUR 729 |
|
Zebrafish Metalloproteinase Inhibitor 2 (TIMP2) Protein |
abx655248-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Metalloproteinase Inhibitor 2 (TIMP2) Protein |
abx655248-50g |
Abbexa |
50 µg |
EUR 5300 |
Zebrafish Metalloproteinase Inhibitor 3 (TIMP3) Protein |
abx655257-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Metalloproteinase Inhibitor 3 (TIMP3) Protein |
abx655257-50g |
Abbexa |
50 µg |
EUR 5300 |
Zebrafish Stromal Cell Derived Factor 1 (SDF1) Protein |
20-abx655150 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Zebrafish TEK Tyrosine Kinase, Endothelial (Tie2) Protein |
20-abx655203 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Zebrafish HSP-70/HSPA9(HeatShock Protein 70) ELISA Kit |
ELK9341-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Zebrafish HSP-70/HSPA9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish HSP-70/HSPA9. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Zebrafish HSP-70/HSPA9, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish HSP-70/HSPA9 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Zebrafish HSP-70/HSPA9(HeatShock Protein 70) ELISA Kit |
ELK9341-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Zebrafish HSP-70/HSPA9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish HSP-70/HSPA9. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Zebrafish HSP-70/HSPA9, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish HSP-70/HSPA9 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Zebrafish Total RNA |
ZFR-270 |
Zyagen |
0.025mg |
EUR 319 |
Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein |
20-abx655292 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein |
abx655292-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein |
abx655292-50g |
Abbexa |
50 µg |
EUR 5300 |
Zebrafish Genomic DNA |
GZ-270 |
Zyagen |
0.025mg |
EUR 177 |
ak2 Antibody (Zebrafish) |
F54506-0.05ML |
NSJ Bioreagents |
0.05 ml |
EUR 140.25 |
|
Description: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. |
ak2 Antibody (Zebrafish) |
F54506-0.2ML |
NSJ Bioreagents |
0.2 ml |
EUR 322.15 |
|
Description: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. |
Ada Antibody (Zebrafish) |
F52652-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). |
Zebrafish Ada Antibody |
F52652-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). |
Zebrafish Cluster Of Differentiation 40 Ligand (CD40L) Protein |
20-abx652963 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Insulin Like Growth Factor Binding Protein 1 (IGFBP1) Protein |
20-abx653853 |
Abbexa |
-
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Zebrafish Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Protein |
20-abx653861 |
Abbexa |
-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
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Zebrafish Insulin Like Growth Factor Binding Protein 1 (IGFBP1) Protein |
abx653853-1ml |
Abbexa |
1 ml |
EUR 2112.5 |
Zebrafish Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Protein |
abx653861-10mg |
Abbexa |
10 mg |
EUR 5300 |
Zebrafish Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Protein |
abx653861-2mg |
Abbexa |
2 mg |
EUR 2112.5 |
Zebrafish Atf4 Antibody |
F52258-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (By similarity). |
Zebrafish Atf4 Antibody |
F52258-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (By similarity). |
Zebrafish Gfap Antibody |
F52537-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Glial fibrillary acidic protein |
Zebrafish LC3B Antibody |
F53289-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: N/A |
Zebrafish LC3B Antibody |
F53289-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: N/A |
Atg5 Antibody (Zebrafish) |
F53381-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Involved in autophagic vesicle formation. |
Atg5 Antibody (Zebrafish) |
F53381-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Involved in autophagic vesicle formation. |
Zebrafish LC3A Antibody |
F53024-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Microtubule-associated protein 1 light chain 3 alpha |
Zebrafish LC3A Antibody |
F53024-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Microtubule-associated protein 1 light chain 3 alpha |
Atg5 Antibody (Zebrafish) |
F53143-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Atg5 is involved in autophagic vesicle formation. |
Zebrafish Thrb Antibody |
R33481-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
|
Description: Additional name(s) for this target protein: Thyroid hormone receptor beta |
Zebrafish Transforming Growth Factor Beta Induced Protein (TGFbI) Protein |
20-abx655306 |
Abbexa |
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
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Zebrafish Transforming Growth Factor Beta Induced Protein (TGFbI) Protein |
abx655306-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Transforming Growth Factor Beta Induced Protein (TGFbI) Protein |
abx655306-50g |
Abbexa |
50 µg |
EUR 5300 |
Zebrafish Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) Protein |
abx655412-10g |
Abbexa |
10 µg |
EUR 2112.5 |
Zebrafish Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) Protein |
abx655412-50g |
Abbexa |
50 µg |
EUR 5300 |
Zebrafish Pax2a Antibody |
F52269-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. |
Zebrafish Pax2a Antibody |
F52269-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. |
S1pr1 Antibody (Zebrafish) |
F52393-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins. |
Gapdh Antibody (Zebrafish) |
F52573-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins (By similarity). |
Zebrafish Gapdh Antibody |
F52573-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins (By similarity). |
Zebrafish Stromal Cell-Derived Factor 1 / SDF1 (CXCL12) Protein |
abx655150-10g |
Abbexa |
10 µg |
EUR 400 |
Zebrafish Stromal Cell-Derived Factor 1 / SDF1 (CXCL12) Protein |
abx655150-50g |
Abbexa |
50 µg |
EUR 587.5 |
Pou3f3a Antibody (Zebrafish) |
F52241-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Transcription factor that may play important roles in patterning the embryonic brain. |
Pou3f3a Antibody (Zebrafish) |
F52241-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Transcription factor that may play important roles in patterning the embryonic brain. |
Zebrafish Patched Antibody |
R35480-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
|
Description: Additional name(s) for this target protein: Zebrafish patched 1, ptc1; ptc1 |
Zebrafish Tissue Inhibitors Of Metalloproteinase 2 (TIMP2) Protein |
20-abx655248 |
Abbexa |
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Zebrafish Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Protein |
20-abx655257 |
Abbexa |
-
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-
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-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Recombinant Zebrafish Metallothionein-2 Protein, His, Yeast-10ug |
QP9826-ye-10ug |
EnQuireBio |
10ug |
EUR 434.4 |
Recombinant Zebrafish Metallothionein-2 Protein, His, Yeast-1mg |
QP9826-ye-1mg |
EnQuireBio |
1mg |
EUR 3296.4 |
Recombinant Zebrafish Metallothionein-2 Protein, His, Yeast-50ug |
QP9826-ye-50ug |
EnQuireBio |
50ug |
EUR 576 |
Gabarapa Antibody (Zebrafish) |
F53276-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: GABA(A) receptor associated protein |
Zebrafish Map1lc3a Antibody |
F53023-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Microtubule-associated protein 1 light chain 3 alpha |
Zebrafish Map1lc3a Antibody |
F53023-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Microtubule-associated protein 1 light chain 3 alpha |
EPDR1 (untagged)-Human ependymin related protein 1 (zebrafish) (EPDR1) |
SC122862 |
Origene Technologies GmbH |
10 µg |
Ask for price |
EE2-responsive networks in different tissues aren’t as comprehensively outlined which is a information hole as regulated networks are anticipated to be tissue-specific. On the horizon, omics research for estrogen-mediated results in fish embody: (1) Establishing conceptual frameworks for incorporating estrogen-responsive networks into environmental monitoring packages; (2) Leveraging in vitro and computational toxicology approaches to determine chemical compounds related to estrogen receptor-mediated results in fish (e.g., male vitellogenin manufacturing); (3) Discovering new tissue-specific estrogen receptor signaling pathways in fish; and (4) Creating quantitative adversarial final result pathway predictive fashions for estrogen signaling.
As we glance forward, analysis into EE2 over the previous a number of a long time can function a template for the array of hormones and endocrine lively substances but to be absolutely characterised or found.