Casting a wide net: use of diverse model organisms to advance toxicology.

Casting a wide net: use of diverse model organisms to advance toxicology.

Toxicology – the research of how chemical compounds work together with organic techniques – has clear relevance to human well being and illness. Persistent publicity to pure and artificial chemical compounds is an unavoidable a part of residing on our planet; but, we perceive little or no concerning the results of publicity to the overwhelming majority of chemical compounds. Whereas epidemiological research can present robust statistical inference linking chemical publicity to illness, analysis in mannequin techniques is crucial to elucidate the mechanisms of motion and to foretell outcomes.

Most analysis in toxicology makes use of a handful of mammalian fashions that symbolize a number of distinct branches of the evolutionary tree. This slender focus constrains the understanding of chemical-induced illness processes and techniques which have developed in response to exposures. We advocate for casting a wider internet in environmental toxicology analysis to make the most of various mannequin techniques, together with zebrafish, and carry out extra mechanistic research of mobile responses to chemical exposures to shift the notion of toxicology as an utilized science to that of a primary science. This more-inclusive perspective will enrich the sector and may stay central to analysis on chemical-induced illness.

Traditionally, analysis in toxicology has utilized non-human mammalian species, notably rats and mice, to check in vivo the results of poisonous publicity on physiology and conduct. Nevertheless, moral issues and the overwhelming enhance within the variety of chemical compounds to be screened has led to a shift away from in vivo work. The decline in in vivo experimentation has been accompanied by a rise in various strategies for detecting and predicting detrimental results: in vitro experimentation and in silico modeling.

But, these new methodologies can’t substitute the necessity for in vivo work on animal physiology and conduct. The event of recent, non-mammalian mannequin techniques exhibits nice promise in restoring our skill to make use of behavioral endpoints in toxicological testing. Of those techniques, the zebrafishDanio rerio, is the mannequin organism for which we’re accumulating sufficient information in vivoin vitro, and in silico to allow us to develop a complete, highthroughput toxicology screening system.

Developmental toxicity of fipronil in early improvement of zebrafish (Danio rerio) larvae: Disrupted vascular formation with angiogenic failure and inhibited neurogenesis.

Fipronil has been extensively utilized in agriculture to forestall aggressive bugs from damaging agricultural merchandise. Fipronil residues flow into within the setting they usually have been detected in non-targeted organisms in aquatic environments. To check the impact of fipronil toxicity on environmental well being, 6 h put up fertilization (hpf) zebrafish embryos have been handled with fipronil for 72 h. LC50 worth was obtained by making use of various concentrations of fipronil to zebrafish embryos for 72 h.

As zebrafish embryos are helpful vertebrate fashions for finding out developmental and genetic findings in toxicology analysis, they have been uncovered to fipronil to check detailed elucidating mechanisms with hazardous finish factors of toxicity. Cell cycle arrest-related apoptosis supported pathological alterations, equivalent to elevated mortality, shortened physique size, and lowered hatchability.

Moreover, noticed coronary heart defects, together with edema and irregular heartbeat have been triggered because of irregular blood circulation. In transgenic zebrafish fashions (fli1:eGFP and olig2:dsRED), disrupted blood vessel formations have been indicated by eGFP+ endothelial cells. Furthermore, neurogenic defects have been noticed by finding out dsRED+ motor neurons and oligodendrocytes. This research demonstrates fipronil accumulation in aquatic setting and its skill to impair important processes, equivalent to angiogenesis and neurogenesis throughout early developmental stage of zebrafish, together with normal developmental toxicity.

Casting a wide net: use of diverse model organisms to advance toxicology.

Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish.

In aquatic toxicology, maybe no pharmaceutical has been investigated extra intensely than 17alpha-ethinylestradiol (EE2), the lively ingredient of the contraception capsule. On the flip of the century, the fields of comparative endocrinology and endocrine disruption analysis witnessed the emergence of omics applied sciences, which have been quickly tailored to characterize potential hazards related to exposures to environmental estrogens, equivalent to EE2.
Since then, vital advances have been made by the scientific neighborhood, and in consequence, a lot has been realized about estrogen receptor signaling in fish from environmental xenoestrogens. Vitellogenin, the egg yolk precursor protein, was recognized as a significant estrogen-responsive gene, establishing itself because the premier biomarker for estrogenic exposures. Omics research have recognized a plethora of estrogen responsive genes, contributing to a wealth of data on estrogen-mediated regulatory networks in teleosts.
There have been ∼40 research that report on transcriptome responses to EE2 in quite a lot of fish species (e.g., zebrafish, fathead minnows, rainbow trout, pipefish, mummichog, stickleback, cod, and others). Information on the liver and testis transcriptome dominate within the literature and have been the topic of many EE2 research, but there stay information gaps for different tissues, such because the spleen, kidney, and pituitary. Inter-laboratory genomics research have revealed transcriptional networks altered by EE2 remedy within the liver; networks associated to amino acid activation and protein folding are elevated by EE2 whereas these associated to xenobiotic metabolism, immune system, circulation, and triglyceride storage are suppressed.

Recombinant Zebrafish Growth Hormone Mutant

7-00574 5µg Ask for price

Recombinant Zebrafish Growth Hormone Mutant

7-00575 50µg Ask for price

Recombinant Zebrafish Growth Hormone Mutant

7-00576 1mg Ask for price

Recombinant Zebrafish GH Protein, Untagged, E.coli-1mg

QP10635-1mg 1mg
EUR 2829.6

Recombinant Zebrafish GH Protein, Untagged, E.coli-10ug

QP10635-10ug 10ug
EUR 186

Recombinant Zebrafish GH Protein, Untagged, E.coli-50ug

QP10635-50ug 50ug
EUR 241.2

Zebrafish Talin (TLN) Protein

20-abx655190
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Growth Hormone Protein

20-abx260620
  • EUR 3483.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 50 ug
  • 5 ug

Zebrafish Cathepsin L (CTSL) Protein

20-abx652813
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Interleukin 15 (IL15) Protein

20-abx653977
  • EUR 1078.80
  • EUR 393.60
  • EUR 3517.20
  • EUR 1312.80
  • EUR 760.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Interleukin 12B (IL12B) Protein

20-abx653962
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Galactosidase Beta (GLb) Protein

20-abx653494
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Zebrafish A1AT Protein (aa 1-124)

VAng-2983Lsx-1mg 1 mg
EUR 3820.8
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2)

Recombinant Zebrafish A1AT Protein (aa 1-124)

VAng-2983Lsx-200g 200 µg
EUR 2337.6
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2)

Recombinant Zebrafish A1AT Protein (aa 1-124)

VAng-2983Lsx-500g 500 µg
EUR 2568
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2)

Recombinant Zebrafish ALCAM Protein (aa 25-507)

VAng-2956Lsx-1mg 1 mg
EUR 6906
Description: Recombinant Zebrafish ALCAM is expressed in E. coli. (Uniprot ID: Q90460)

Recombinant Zebrafish ALCAM Protein (aa 25-507)

VAng-2956Lsx-500g 500 µg
EUR 4233.6
Description: Recombinant Zebrafish ALCAM is expressed in E. coli. (Uniprot ID: Q90460)

Recombinant Zebrafish Cxadr Protein (aa 23-241)

VAng-Cr4512-1mgEcoli 1 mg (E. coli)
EUR 4876.8
Description: Zebrafish Coxsackievirus and adenovirus receptor homolog (cxadr), recombinant protein.

Recombinant Zebrafish Cxadr Protein (aa 23-241)

VAng-Cr4512-500gEcoli 500 µg (E. coli)
EUR 3261.6
Description: Zebrafish Coxsackievirus and adenovirus receptor homolog (cxadr), recombinant protein.

Zebrafish Creatine Kinase, Muscle (CKM) Protein

20-abx653069
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Zebrafish VEGF165 Protein (aa 1-188)

VAng-Cr4056-100g 100 µg
EUR 2841.6
Description: Recombinant Zebrafish VEGF165 Protein (Met1-Arg188) was expressed in Baculovirus-Insect Cells, with a molecular weight of 19.2 kDa. (Accession ID: O73682)

Recombinant Zebrafish VEGF165 Protein (aa 1-188)

VAng-Cr4056-5g 5 µg
EUR 456
Description: Recombinant Zebrafish VEGF165 Protein (Met1-Arg188) was expressed in Baculovirus-Insect Cells, with a molecular weight of 19.2 kDa. (Accession ID: O73682)

Zebrafish Bone Morphogenetic Protein 4 (BMP4) Protein

20-abx652682
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Id1 Rbt pAb, Protein A purified, 25UG

A014-25UG 25UG
EUR 510

Zebrafish Anti-Mullerian Hormone (AMH) Protein (BSA)

20-abx651052
  • EUR 376.80
  • EUR 243.60
  • EUR 978.00
  • EUR 427.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Anti-Mullerian Hormone (AMH) Protein (OVA)

20-abx651053
  • EUR 376.80
  • EUR 243.60
  • EUR 978.00
  • EUR 427.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Fibroblast Growth Factor 6 (FGF6) Protein

20-abx653400
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ada Antibody (Zebrafish)

F52652-0.08ML 0.08 ml
EUR 140.25
Description: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity).

Zebrafish Ada Antibody

F52652-0.4ML 0.4 ml
EUR 322.15
Description: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity).

ak2 Antibody (Zebrafish)

F54506-0.05ML 0.05 ml
EUR 140.25
Description: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.

ak2 Antibody (Zebrafish)

F54506-0.2ML 0.2 ml
EUR 322.15
Description: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.

Zebrafish Gonadotropin Releasing Hormone (GnRH) Protein

20-abx653622
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish LC3A Antibody

F53024-0.08ML 0.08 ml
EUR 140.25
Description: Microtubule-associated protein 1 light chain 3 alpha

Zebrafish LC3A Antibody

F53024-0.4ML 0.4 ml
EUR 322.15
Description: Microtubule-associated protein 1 light chain 3 alpha

Zebrafish LC3B Antibody

F53289-0.08ML 0.08 ml
EUR 140.25

Zebrafish LC3B Antibody

F53289-0.4ML 0.4 ml
EUR 322.15

Zebrafish Atf4 Antibody

F52258-0.08ML 0.08 ml
EUR 140.25
Description: Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (By similarity).

Zebrafish Atf4 Antibody

F52258-0.4ML 0.4 ml
EUR 322.15
Description: Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (By similarity).

Zebrafish Gfap Antibody

F52537-0.4ML 0.4 ml
EUR 322.15
Description: Glial fibrillary acidic protein

Atg5 Antibody (Zebrafish)

F53143-0.08ML 0.08 ml
EUR 140.25
Description: Atg5 is involved in autophagic vesicle formation.

Atg5 Antibody (Zebrafish)

F53381-0.08ML 0.08 ml
EUR 140.25
Description: Involved in autophagic vesicle formation.

Atg5 Antibody (Zebrafish)

F53381-0.4ML 0.4 ml
EUR 322.15
Description: Involved in autophagic vesicle formation.

Zebrafish Thrb Antibody

R33481-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Thyroid hormone receptor beta

Zebrafish Pax2a Antibody

F52269-0.08ML 0.08 ml
EUR 140.25
Description: Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation.

Zebrafish Pax2a Antibody

F52269-0.4ML 0.4 ml
EUR 322.15
Description: Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation.

S1pr1 Antibody (Zebrafish)

F52393-0.08ML 0.08 ml
EUR 140.25
Description: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.

Gapdh Antibody (Zebrafish)

F52573-0.08ML 0.08 ml
EUR 140.25
Description: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins (By similarity).

Zebrafish Gapdh Antibody

F52573-0.4ML 0.4 ml
EUR 322.15
Description: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins (By similarity).

Zebrafish Stromal Cell Derived Factor 1 (SDF1) Protein

20-abx655150
  • EUR 844.80
  • EUR 343.20
  • EUR 2598.00
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish TEK Tyrosine Kinase, Endothelial (Tie2) Protein

20-abx655203
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pou3f3a Antibody (Zebrafish)

F52241-0.08ML 0.08 ml
EUR 140.25
Description: Transcription factor that may play important roles in patterning the embryonic brain.

Pou3f3a Antibody (Zebrafish)

F52241-0.4ML 0.4 ml
EUR 322.15
Description: Transcription factor that may play important roles in patterning the embryonic brain.

Zebrafish Patched Antibody

R35480-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Zebrafish patched 1, ptc1; ptc1

Zebrafish Map1lc3a Antibody

F53023-0.08ML 0.08 ml
EUR 140.25
Description: Microtubule-associated protein 1 light chain 3 alpha

Zebrafish Map1lc3a Antibody

F53023-0.4ML 0.4 ml
EUR 322.15
Description: Microtubule-associated protein 1 light chain 3 alpha

Gabarapa Antibody (Zebrafish)

F53276-0.08ML 0.08 ml
EUR 140.25
Description: GABA(A) receptor associated protein

Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein

20-abx655292
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Cluster Of Differentiation 40 Ligand (CD40L) Protein

20-abx652963
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Nori® Zebrafish 14-3-3 ELISA Kit

GR206178 96-well
EUR 461

Zebrafish Beclin-1 Antibody

F53282-0.4ML 0.4 ml
EUR 322.15
Description: Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.

Zebrafish beta Actin Antibody

F52293-0.08ML 0.08 ml
EUR 140.25
Description: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Expression of beta Actin is strongest in lymph tissues with weaker expression seen in muscle and heart.

Zebrafish beta Actin Antibody

F52293-0.4ML 0.4 ml
EUR 322.15
Description: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Expression of beta Actin is strongest in lymph tissues with weaker expression seen in muscle and heart.

Beclin-1 Antibody (Zebrafish)

F53282-0.08ML 0.08 ml
EUR 140.25
Description: Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.

Pou5f1 Antibody OCT4 (Zebrafish)

F52574-0.08ML 0.08 ml
EUR 140.25
Description: Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t- POU2 causes developmental retardation or arrest before gastrulation.

Anti-Thrb (zebrafish) antibody

STJ71268 100 µg
EUR 430.8

Anti-Her6 (zebrafish) antibody

STJ71294 100 µg
EUR 312

Zebrafish Insulin Like Growth Factor Binding Protein 1 (IGFBP1) Protein

20-abx653853
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Protein

20-abx653861
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Anti-Hand2 (zebrafish) antibody

STJ71256 100 µg
EUR 312

Anti-Six3b (zebrafish) antibody

STJ71263 100 µg
EUR 312

Anti-Sox9a (zebrafish) antibody

STJ71264 100 µg
EUR 312

Anti-Sox9b (zebrafish) antibody

STJ71265 100 µg
EUR 312

Anti-Timp2 (zebrafish) antibody

STJ71270 100 µg
EUR 312

Anti-Atoh7 (zebrafish) antibody

STJ71272 100 µg
EUR 312

Anti-Ptf1a (zebrafish) antibody

STJ71274 100 µg
EUR 312

Zebrafish Transforming Growth Factor Beta Induced Protein (TGFbI) Protein

20-abx655306
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Nori® Zebrafish ProBNP ELISA Kit

GR206089 96-well
EUR 461

Anti-Tfap2a (zebrafish) antibody

STJ71254 100 µg
EUR 312

Anti-Ascl1a (zebrafish) antibody

STJ71255 100 µg
EUR 312

Anti-Timp2L (zebrafish) antibody

STJ71271 100 µg
EUR 312

Anti-Cxcr4b (zebrafish) antibody

STJ71293 100 µg
EUR 312

Nori® Zebrafish 14-3-3 eta ELISA Kit

GR206048 96-well
EUR 461

Anti-Notch1a (zebrafish) antibody

STJ71260 100 µg
EUR 312

Anti-Notch1b (zebrafish) antibody

STJ71261 100 µg
EUR 312

Nori® Zebrafish IgA ELISA Kit

GR206003 96-well
EUR 461

Nori® Zebrafish HGF ELISA Kit

GR206032 96-well
EUR 461

Nori® Zebrafish CRP ELISA Kit

GR206040 96-well
EUR 461

Nori® Zebrafish EGF ELISA Kit

GR206049 96-well
EUR 461

Nori® Zebrafish BNP ELISA Kit

GR206084 96-well
EUR 461

Nori® Zebrafish ANP ELISA Kit

GR206085 96-well
EUR 461

Nori® Zebrafish ACE ELISA Kit

GR206092 96-well
EUR 461

Nori® Zebrafish tPA ELISA Kit

GR206112 96-well
EUR 461

Nori® Zebrafish AGP ELISA Kit

GR206130 96-well
EUR 461

Nori® Zebrafish IgG ELISA Kit

GR206141 96-well
EUR 461

Nori® Zebrafish IgE ELISA Kit

GR206142 96-well
EUR 461

Nori® Zebrafish IgM ELISA Kit

GR206143 96-well
EUR 461

Zebrafish Tissue Inhibitors Of Metalloproteinase 2 (TIMP2) Protein

20-abx655248
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Protein

20-abx655257
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Zebrafish Metallothionein-2 Protein, His, Yeast-10ug

QP9826-ye-10ug 10ug
EUR 434.4

Recombinant Zebrafish Metallothionein-2 Protein, His, Yeast-1mg

QP9826-ye-1mg 1mg
EUR 3296.4

Recombinant Zebrafish Metallothionein-2 Protein, His, Yeast-50ug

QP9826-ye-50ug 50ug
EUR 576

Nicalin Homolog (Zebrafish) Antibody

20-abx114104
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Nori® Zebrafish BMP1 ELISA Kit

GR206005 96-well
EUR 461

Nori® Zebrafish BDNF ELISA Kit

GR206015 96-well
EUR 461

Nori® Zebrafish UCP2 ELISA Kit

GR206016 96-well
EUR 461

Nori® Zebrafish PIGF ELISA Kit

GR206033 96-well
EUR 461

Nori® Zebrafish CNTF ELISA Kit

GR206036 96-well
EUR 461

Nori® Zebrafish PDGF ELISA Kit

GR206039 96-well
EUR 461

Nori® Zebrafish FGF7 ELISA Kit

GR206046 96-well
EUR 461

Nori® Zebrafish BMP2 ELISA Kit

GR206056 96-well
EUR 461

Nori® Zebrafish BMP3 ELISA Kit

GR206057 96-well
EUR 461

Nori® Zebrafish BMP4 ELISA Kit

GR206058 96-well
EUR 461

Nori® Zebrafish BMP5 ELISA Kit

GR206059 96-well
EUR 461

Nori® Zebrafish BMP6 ELISA Kit

GR206060 96-well
EUR 461

Nori® Zebrafish BMP7 ELISA Kit

GR206061 96-well
EUR 461

Nori® Zebrafish IGF2 ELISA Kit

GR206062 96-well
EUR 461

Nori® Zebrafish GPBB ELISA Kit

GR206083 96-well
EUR 461

Nori® Zebrafish SAA1 ELISA Kit

GR206096 96-well
EUR 461

Nori® Zebrafish SAA2 ELISA Kit

GR206097 96-well
EUR 461

Nori® Zebrafish SAA3 ELISA Kit

GR206098 96-well
EUR 461

Nori® Zebrafish SAA4 ELISA Kit

GR206099 96-well
EUR 461

Nori® Zebrafish CCL1 ELISA Kit

GR206102 96-well
EUR 461

Nori® Zebrafish CCL2 ELISA Kit

GR206103 96-well
EUR 461
EE2-responsive networks in different tissues aren’t as comprehensively outlined which is a information hole as regulated networks are anticipated to be tissue-specific. On the horizon, omics research for estrogen-mediated results in fish embody: (1) Establishing conceptual frameworks for incorporating estrogen-responsive networks into environmental monitoring packages; (2) Leveraging in vitro and computational toxicology approaches to determine chemical compounds related to estrogen receptor-mediated results in fish (e.g., male vitellogenin manufacturing); (3) Discovering new tissue-specific estrogen receptor signaling pathways in fish; and (4) Creating quantitative adversarial final result pathway predictive fashions for estrogen signaling.
As we glance forward, analysis into EE2 over the previous a number of a long time can function a template for the array of hormones and endocrine lively substances but to be absolutely characterised or found.

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