Casting a wide net: use of diverse model organisms to advance toxicology.

Casting a wide net: use of diverse model organisms to advance toxicology.

Toxicology – the research of how chemical compounds work together with organic techniques – has clear relevance to human well being and illness. Persistent publicity to pure and artificial chemical compounds is an unavoidable a part of residing on our planet; but, we perceive little or no concerning the results of publicity to the overwhelming majority of chemical compounds. Whereas epidemiological research can present robust statistical inference linking chemical publicity to illness, analysis in mannequin techniques is crucial to elucidate the mechanisms of motion and to foretell outcomes.

Most analysis in toxicology makes use of a handful of mammalian fashions that symbolize a number of distinct branches of the evolutionary tree. This slender focus constrains the understanding of chemical-induced illness processes and techniques which have developed in response to exposures. We advocate for casting a wider internet in environmental toxicology analysis to make the most of various mannequin techniques, together with zebrafish, and carry out extra mechanistic research of mobile responses to chemical exposures to shift the notion of toxicology as an utilized science to that of a primary science. This more-inclusive perspective will enrich the sector and may stay central to analysis on chemical-induced illness.

Traditionally, analysis in toxicology has utilized non-human mammalian species, notably rats and mice, to check in vivo the results of poisonous publicity on physiology and conduct. Nevertheless, moral issues and the overwhelming enhance within the variety of chemical compounds to be screened has led to a shift away from in vivo work. The decline in in vivo experimentation has been accompanied by a rise in various strategies for detecting and predicting detrimental results: in vitro experimentation and in silico modeling.

But, these new methodologies can’t substitute the necessity for in vivo work on animal physiology and conduct. The event of recent, non-mammalian mannequin techniques exhibits nice promise in restoring our skill to make use of behavioral endpoints in toxicological testing. Of those techniques, the zebrafishDanio rerio, is the mannequin organism for which we’re accumulating sufficient information in vivoin vitro, and in silico to allow us to develop a complete, highthroughput toxicology screening system.

Developmental toxicity of fipronil in early improvement of zebrafish (Danio rerio) larvae: Disrupted vascular formation with angiogenic failure and inhibited neurogenesis.

Fipronil has been extensively utilized in agriculture to forestall aggressive bugs from damaging agricultural merchandise. Fipronil residues flow into within the setting they usually have been detected in non-targeted organisms in aquatic environments. To check the impact of fipronil toxicity on environmental well being, 6 h put up fertilization (hpf) zebrafish embryos have been handled with fipronil for 72 h. LC50 worth was obtained by making use of various concentrations of fipronil to zebrafish embryos for 72 h.

As zebrafish embryos are helpful vertebrate fashions for finding out developmental and genetic findings in toxicology analysis, they have been uncovered to fipronil to check detailed elucidating mechanisms with hazardous finish factors of toxicity. Cell cycle arrest-related apoptosis supported pathological alterations, equivalent to elevated mortality, shortened physique size, and lowered hatchability.

Moreover, noticed coronary heart defects, together with edema and irregular heartbeat have been triggered because of irregular blood circulation. In transgenic zebrafish fashions (fli1:eGFP and olig2:dsRED), disrupted blood vessel formations have been indicated by eGFP+ endothelial cells. Furthermore, neurogenic defects have been noticed by finding out dsRED+ motor neurons and oligodendrocytes. This research demonstrates fipronil accumulation in aquatic setting and its skill to impair important processes, equivalent to angiogenesis and neurogenesis throughout early developmental stage of zebrafish, together with normal developmental toxicity.

Casting a wide net: use of diverse model organisms to advance toxicology.

Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish.

In aquatic toxicology, maybe no pharmaceutical has been investigated extra intensely than 17alpha-ethinylestradiol (EE2), the lively ingredient of the contraception capsule. On the flip of the century, the fields of comparative endocrinology and endocrine disruption analysis witnessed the emergence of omics applied sciences, which have been quickly tailored to characterize potential hazards related to exposures to environmental estrogens, equivalent to EE2.
Since then, vital advances have been made by the scientific neighborhood, and in consequence, a lot has been realized about estrogen receptor signaling in fish from environmental xenoestrogens. Vitellogenin, the egg yolk precursor protein, was recognized as a significant estrogen-responsive gene, establishing itself because the premier biomarker for estrogenic exposures. Omics research have recognized a plethora of estrogen responsive genes, contributing to a wealth of data on estrogen-mediated regulatory networks in teleosts.
There have been ∼40 research that report on transcriptome responses to EE2 in quite a lot of fish species (e.g., zebrafish, fathead minnows, rainbow trout, pipefish, mummichog, stickleback, cod, and others). Information on the liver and testis transcriptome dominate within the literature and have been the topic of many EE2 research, but there stay information gaps for different tissues, such because the spleen, kidney, and pituitary. Inter-laboratory genomics research have revealed transcriptional networks altered by EE2 remedy within the liver; networks associated to amino acid activation and protein folding are elevated by EE2 whereas these associated to xenobiotic metabolism, immune system, circulation, and triglyceride storage are suppressed.

Zebrafish Growth Hormone Mutant Protein

20-abx260619
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 50 ug
  • 5 ug

Zebrafish Somatotropin, G113R mutant (GH1) Protein

abx260619-10g 10 µg
EUR 325

Zebrafish Somatotropin, G113R mutant (GH1) Protein

abx260619-2g 2 µg
EUR 225

Zebrafish Growth Hormone mutant (G119R) Recombinant Protein

500-023 50 µg
EUR 278.25
Description: Recombinant zebrafish growth hormone mutant G119R (zbGH mutant) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton.

Zebrafish Growth Hormone mutant (G119R) Recombinant Protein

500-023S 10 µg
EUR 178.5
Description: Recombinant zebrafish growth hormone mutant G119R (zbGH mutant) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton.

Zebrafish growth hormone mutant G119R

MBS400075-001mg 0.01mg
EUR 185

Zebrafish growth hormone mutant G119R

MBS400075-005mg 0.05mg
EUR 275

Zebrafish growth hormone mutant G119R

MBS400075-01mg 0.1mg
EUR 370

Zebrafish growth hormone mutant G119R

MBS400075-05mg 0.5mg
EUR 940

Zebrafish growth hormone mutant G119R

MBS400075-1mg 1mg
EUR 1500

Recombinant Zebrafish Growth Hormone Mutant

7-00574 5µg Ask for price

Recombinant Zebrafish Growth Hormone Mutant

7-00575 50µg Ask for price

Recombinant Zebrafish Growth Hormone Mutant

7-00576 1mg Ask for price

Growth Hormone Mutant Zebrafish Recombinant

rAP-2287 Inquiry Ask for price

Recombinant Zebrafish Growth Hormone Mutant

cyt-709-10g 10µg
EUR 60

Recombinant Zebrafish Growth Hormone Mutant

cyt-709-1mg 1mg
EUR 2300

Recombinant Zebrafish Growth Hormone Mutant

cyt-709-50g 50µg
EUR 145

Recombinant Zebrafish Growth Hormone Mutant

MBS144094-001mg 0.01mg
EUR 240

Recombinant Zebrafish Growth Hormone Mutant

MBS144094-005mg 0.05mg
EUR 310

Recombinant Zebrafish Growth Hormone Mutant

MBS144094-1mg 1mg
EUR 2465

Recombinant Zebrafish Growth Hormone Mutant

MBS144094-5x1mg 5x1mg
EUR 10760

OPPA02407-5UG - GH Zebrafish Protein

OPPA02407-5UG 5ug
EUR 70

Recombinant Zebrafish GH Protein, Untagged, E.coli-1mg

QP10635-1mg 1mg
EUR 2829.6

Recombinant Zebrafish GH Protein, Untagged, E.coli-10ug

QP10635-10ug 10ug
EUR 186

Recombinant Zebrafish GH Protein, Untagged, E.coli-50ug

QP10635-50ug 50ug
EUR 241.2

Zebrafish GH(Growth Hormone) ELISA Kit

ELK9404-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Zebrafish GH protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish GH. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish GH in the samples is then determined by comparing the OD of the samples to the standard curve.

Zebrafish GH(Growth Hormone) ELISA Kit

ELK9404-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Zebrafish GH protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish GH. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish GH in the samples is then determined by comparing the OD of the samples to the standard curve.

Zebrafish Talin (TLN) Protein

20-abx655190
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Talin (TLN) Protein

abx655190-10g 10 µg
EUR 2112.5

Zebrafish Talin (TLN) Protein

abx655190-50g 50 µg
EUR 5300

Zebrafish Growth Hormone Protein

20-abx260620
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 50 ug
  • 5 ug

Recombinant Zebrafish IL8 Protein

IL8-4401Z 5 µg
EUR 398.4
Description: Store at -20 centigrade.

Recombinant Zebrafish IL13 Protein

IL13-4328Z 100 µg
EUR 1198.4
Description: Store at -20 centigrade.

Zebrafish Somatotropin (GH1) Protein

abx260620-10g 10 µg
EUR 325

Zebrafish Somatotropin (GH1) Protein

abx260620-2g 2 µg
EUR 225

Recombinant Zebrafish tnfa Protein

tnfa-4382Z 100 µg
EUR 1498.4
Description: Store at -20 centigrade.

Recombinant zebrafish VEGFA protein

MK0774Z 10ug
EUR 319.2
Description: N/A

Zebrafish Cathepsin L (CTSL) Protein

20-abx652813
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Danio rerio (zebrafish) VEGFA Protein

E40PZE003 20ug
EUR 495

Zebrafish Cathepsin L1 (CTSL) Protein

abx652813-5mg 5 mg
EUR 5300

Zebrafish Interleukin 15 (IL15) Protein

20-abx653977
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Interleukin 15 (IL15) Protein

abx653977-100g 100 µg
EUR 8012.5

Zebrafish Interleukin 15 (IL15) Protein

abx653977-200g 200 µg Ask for price

Zebrafish Interleukin 15 (IL15) Protein

abx653977-50g 50 µg
EUR 3200

Zebrafish Interleukin 12B (IL12B) Protein

20-abx653962
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Interleukin 12B (IL12B) Protein

abx653962-5mg 5 mg
EUR 2112.5

Zebrafish Galactosidase Beta (GLb) Protein

20-abx653494
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Beta-Galactosidase (GLB1) Protein

abx653494-100g 100 µg
EUR 5300

Zebrafish Beta-Galactosidase (GLB1) Protein

abx653494-200g 200 µg Ask for price

Zebrafish Beta-Galactosidase (GLB1) Protein

abx653494-50g 50 µg
EUR 2112.5

Zebrafish Growth Hormone Recombinant Protein

500-022 50 µg
EUR 278.25
Description: Recombinant zebrafish growth hormone (zbGH) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton.

Zebrafish Growth Hormone Recombinant Protein

500-022S 10 µg
EUR 178.5
Description: Recombinant zebrafish growth hormone (zbGH) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton.

Recombinant Zebrafish A1AT Protein (aa 1-124)

VAng-2983Lsx-1mg 1 mg
EUR 3820.8
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2)

Recombinant Zebrafish A1AT Protein (aa 1-124)

VAng-2983Lsx-200g 200 µg
EUR 2337.6
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2)

Recombinant Zebrafish A1AT Protein (aa 1-124)

VAng-2983Lsx-500g 500 µg
EUR 2568
Description: Recombinant Zebrafish Alpha 1 Antitrypsin Antigen is expressed in E. coli. (Uniprot ID: Q1L8X2)

Recombinant Zebrafish ALCAM Protein (aa 25-507)

VAng-2956Lsx-1mg 1 mg
EUR 6906
Description: Recombinant Zebrafish ALCAM is expressed in E. coli. (Uniprot ID: Q90460)

Recombinant Zebrafish ALCAM Protein (aa 25-507)

VAng-2956Lsx-500g 500 µg
EUR 4233.6
Description: Recombinant Zebrafish ALCAM is expressed in E. coli. (Uniprot ID: Q90460)

Recombinant Zebrafish Cxadr Protein (aa 23-241)

VAng-Cr4512-1mgEcoli 1 mg (E. coli)
EUR 4876.8
Description: Zebrafish Coxsackievirus and adenovirus receptor homolog (cxadr), recombinant protein.

Recombinant Zebrafish Cxadr Protein (aa 23-241)

VAng-Cr4512-500gEcoli 500 µg (E. coli)
EUR 3261.6
Description: Zebrafish Coxsackievirus and adenovirus receptor homolog (cxadr), recombinant protein.

Zebrafish Creatine Kinase, Muscle (CKM) Protein

20-abx653069
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Creatine Kinase, Muscle (CKM) Protein

abx653069-100g 100 µg
EUR 5300

Zebrafish Creatine Kinase, Muscle (CKM) Protein

abx653069-200g 200 µg Ask for price

Zebrafish Creatine Kinase, Muscle (CKM) Protein

abx653069-50g 50 µg
EUR 2112.5

Zebrafish Bone Morphogenetic Protein 4 (BMP4) Protein

20-abx652682
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Bone Morphogenetic Protein 4 (BMP4) Protein

abx652682-5mg 5 mg
EUR 537.5

Recombinant Zebrafish VEGF165 Protein (aa 1-188)

VAng-Cr4056-100g 100 µg
EUR 2841.6
Description: Recombinant Zebrafish VEGF165 Protein (Met1-Arg188) was expressed in Baculovirus-Insect Cells, with a molecular weight of 19.2 kDa. (Accession ID: O73682)

Recombinant Zebrafish VEGF165 Protein (aa 1-188)

VAng-Cr4056-5g 5 µg
EUR 456
Description: Recombinant Zebrafish VEGF165 Protein (Met1-Arg188) was expressed in Baculovirus-Insect Cells, with a molecular weight of 19.2 kDa. (Accession ID: O73682)

Danio rerio (zebrafish) efnb2a Protein, His Tag

E40PZE001 20ug
EUR 495

Danio rerio (zebrafish) BMP-2 Protein, Fc Tag

E40PZE002 20ug
EUR 495

Recombinant Zebrafish CRP protein, N-His Tag

IMP-2254 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish LHb protein, N-His Tag

IMP-3855 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish IL22 Protein, His-tagged

IL22-60Z 50ug
EUR 255.2
Description: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Recombinant Zebrafish TNFa protein, N-His Tag

IMP-2298 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish IL1b protein, N-His Tag

IMP-2862 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish TSHb protein, N-His Tag

IMP-3851 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish RELA protein, N-His Tag

IMP-3958 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish IL10 protein, N-His Tag

IMP-4121 10µg
EUR 432
Description: Recombinant Proteins

Recombinant Zebrafish IL15 protein, N-His Tag

IMP-4189 10µg
EUR 432
Description: Recombinant Proteins

Zebrafish Id1 Rbt pAb, Protein A purified, 25UG

A014-25UG 25UG
EUR 510

Recombinant Zebrafish igfbp7 protein, N-His tag

MBS1562859-005mg 0.05mg
EUR 320

Recombinant Zebrafish igfbp7 protein, N-His tag

MBS1562859-01mg 0.1mg
EUR 410

Recombinant Zebrafish igfbp7 protein, N-His tag

MBS1562859-5x01mg 5x0.1mg
EUR 1520

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

MBS8123287-002mg 0.02mg
EUR 275

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

MBS8123287-01mg 0.1mg
EUR 560

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

MBS8123287-5x01mg 5x0.1mg
EUR 2370

Zebrafish Anti-Mullerian Hormone (AMH) Protein (BSA)

20-abx651052
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Anti-Mullerian Hormone (AMH) Protein (OVA)

20-abx651053
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Fibroblast Growth Factor 6 (FGF6) Protein

20-abx653400
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Fibroblast Growth Factor 6 (FGF6) Protein

abx653400-5mg 5 mg
EUR 5300

OPCA02179-1MG - D2HGDH Recombinant Protein (Zebrafish)

OPCA02179-1MG 1mg
EUR 2469

Zebrafish Gonadotropin Releasing Hormone (GnRH) Protein

20-abx653622
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Angiopoietin-1 Receptor / TIE2 (TEK) Protein

abx655203-10g 10 µg
EUR 2112.5

Zebrafish Angiopoietin-1 Receptor / TIE2 (TEK) Protein

abx655203-50g 50 µg
EUR 5300

Recombinant Zebrafish TEK protein, N-His-GST Tag

IMP-2157 10µg
EUR 432
Description: Recombinant Proteins

OPCA02179-100UG - D2HGDH Recombinant Protein (Zebrafish)

OPCA02179-100UG 100ug
EUR 729

Zebrafish Metalloproteinase Inhibitor 2 (TIMP2) Protein

abx655248-10g 10 µg
EUR 2112.5

Zebrafish Metalloproteinase Inhibitor 2 (TIMP2) Protein

abx655248-50g 50 µg
EUR 5300

Zebrafish Metalloproteinase Inhibitor 3 (TIMP3) Protein

abx655257-10g 10 µg
EUR 2112.5

Zebrafish Metalloproteinase Inhibitor 3 (TIMP3) Protein

abx655257-50g 50 µg
EUR 5300

Protein moonraker isoform X1 Mouse mAb for zebrafish

MBS435332-005mL 0.05mL
EUR 365

Protein moonraker isoform X1 Mouse mAb for zebrafish

MBS435332-02mL 0.2mL
EUR 580

Protein moonraker isoform X1 Mouse mAb for zebrafish

MBS435332-5x02mL 5x0.2mL
EUR 2280

Zebrafish TEK Tyrosine Kinase, Endothelial (Tie2) Protein

20-abx655203
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Stromal Cell Derived Factor 1 (SDF1) Protein

20-abx655150
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish HSP-70/HSPA9(HeatShock Protein 70) ELISA Kit

ELK9341-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Zebrafish HSP-70/HSPA9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish HSP-70/HSPA9. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Zebrafish HSP-70/HSPA9, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish HSP-70/HSPA9 in the samples is then determined by comparing the OD of the samples to the standard curve.

Zebrafish HSP-70/HSPA9(HeatShock Protein 70) ELISA Kit

ELK9341-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Zebrafish HSP-70/HSPA9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Zebrafish HSP-70/HSPA9. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Zebrafish HSP-70/HSPA9, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Zebrafish HSP-70/HSPA9 in the samples is then determined by comparing the OD of the samples to the standard curve.

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc Tag)

MBS8123285-01mg 0.1mg
EUR 395

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc Tag)

MBS8123285-5x01mg 5x0.1mg
EUR 1635

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His Tag)

MBS8123286-02mg 0.2mg
EUR 560

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His Tag)

MBS8123286-5x02mg 5x0.2mg
EUR 2370

Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein

20-abx655292
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein

abx655292-10g 10 µg
EUR 2112.5

Zebrafish Transforming Growth Factor Beta 1 (TGFb1) Protein

abx655292-50g 50 µg
EUR 5300

Vitellogenin (zebrafish)

MBS603311-01mL 0.1mL
EUR 635

Vitellogenin (zebrafish)

MBS603311-5x01mL 5x0.1mL
EUR 2710

Vitellogenin (zebrafish)

MBS603495-01mL 0.1mL
EUR 655

Vitellogenin (zebrafish)

MBS603495-5x01mL 5x0.1mL
EUR 2805

Vitellogenin (zebrafish)

MBS600923-01mL 0.1mL
EUR 655

Vitellogenin (zebrafish)

MBS600923-5x01mL 5x0.1mL
EUR 2805

Active Recombinant Zebrafish VEGF165 Protein, FITC conjugated

VEGF165-1026ZF 20ug- 50ug- 100ug Ask for price
Description: Store it under sterile conditions at -20 to-70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Zebrafish Total RNA

ZFR-270 0.025mg
EUR 319

A-kinase anchor protein 9-like Mouse mAb for zebrafish

MBS435352-005mL 0.05mL
EUR 365

A-kinase anchor protein 9-like Mouse mAb for zebrafish

MBS435352-02mL 0.2mL
EUR 580
EE2-responsive networks in different tissues aren’t as comprehensively outlined which is a information hole as regulated networks are anticipated to be tissue-specific. On the horizon, omics research for estrogen-mediated results in fish embody: (1) Establishing conceptual frameworks for incorporating estrogen-responsive networks into environmental monitoring packages; (2) Leveraging in vitro and computational toxicology approaches to determine chemical compounds related to estrogen receptor-mediated results in fish (e.g., male vitellogenin manufacturing); (3) Discovering new tissue-specific estrogen receptor signaling pathways in fish; and (4) Creating quantitative adversarial final result pathway predictive fashions for estrogen signaling.
As we glance forward, analysis into EE2 over the previous a number of a long time can function a template for the array of hormones and endocrine lively substances but to be absolutely characterised or found.

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>